Thrift Stores in Cape Girardeau, Missouri

Listing data updated November 19, 2025.

Cape Girardeau, Missouri has 6 thrift stores listed in our directory, from charity shops and consignment stores to vintage boutiques.

Every listing below includes the address and phone number where available, so you can plan a thrift route through Cape Girardeau before you go. Check individual store pages for hours, directions, nearby shops, and live Loot Map deals.

6 Thrift Stores in Cape Girardeau

  1. Le Garret - 19 N. Main Street Booth #18 Upstairs, Cape Girardeau, MO 63701
  2. Goodwill Store and Donation Center - 250 S Silver Springs Rd, Cape Girardeau, MO 63703 - +1 573-651-4690
  3. Teen Challenge Thrift Store - 61 Clark St, Cape Girardeau, MO 63701 - +1 573-651-4510
  4. Once Upon A Child - Cape Girardeau, MO - 760 S Kingshighway # L, Cape Girardeau, MO 63703 - +1 573-803-5437
  5. Habitat For Humanity ReStore - 501 S Kingshighway, Cape Girardeau, MO 63703 - +1 573-651-9080
  6. Second Chance's Welcome llc - 1113 S Sprigg St, Cape Girardeau, MO 63703 - +1 573-200-3616

Thrift Shopping in Cape Girardeau: Common Questions

How many thrift stores are in Cape Girardeau?

There are 6 thrift stores listed in Cape Girardeau, Missouri, including charity shops, consignment stores, and vintage boutiques.

Is there a Goodwill in Cape Girardeau?

Yes — Cape Girardeau has a Goodwill location. See the store list above for the address and phone number.

What is the best day to go thrifting in Cape Girardeau?

Most thrift stores restock early in the week after weekend donations, so Monday through Wednesday mornings usually have the freshest selection. Call ahead to confirm hours before you go.

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