Children's Cancer Society Thrift Store

The Children's Cancer Society Thrift Store on Savannah Highway serves a vital mission while providing Charleston shoppers with an exceptional thrift experience. Located at 2241 Savannah Hwy in Charleston, South Carolina, this nonprofit thrift store channels 100% of its proceeds directly to supporting local children battling cancer and their families. What sets this store apart is the meaningful impact behind every purchase—shoppers know they're not just finding great deals, but also helping provide financial assistance, emotional support, and essential resources to families facing childhood cancer in the Lowcountry. The store has become a beloved fixture in the West Ashley community, attracting both dedicated bargain hunters and compassionate shoppers who want their dollars to make a difference. With a constantly rotating inventory of donated items and a welcoming atmosphere maintained by dedicated staff and volunteers, the Children's Cancer Society Thrift Store offers that perfect combination of treasure-hunting excitement and community contribution that makes thrift shopping truly rewarding.